Basic Instructions falls somewhere in the middle. It's got characters in their settings, but it does not provide any depth to them. It lacks a sense of understanding or identifying with characters -- the way you do when you see something and imagine that it could well be straight out of that particular comic strip. I can observe something at office and call it a Dilbert moment. Characters make strips funnier, and some times they alone make the strip funny.
I doubt that the above strip would appear as funny if I came across it on xkdc. Watterson afforded himself so much breadth and depth within the boundaries of 6yr old that it boggles my mind. That's why I believe Calvin and Hobbes was the best comic strip ever created, yes better than Dilbert. Others tried to play in the similar setting of childhood and couldn't score at all. Dennis the menace often comes across as an adult's contrived view of a child's mind. Tiger hurts my brain. With his views on politics, society and science, with Spaceman Spiff, Stupendous Man, dinosaurs and scientific inventions, Calvin blazed a trail. There's no one else within miles of it.
The comic medium makes it possible to capture imagination and present allegories without sounding ludicrous or out of place. How can a necktie always point up? What's with the menagerie in the office? Few cartoonists grab this opportunity. Perhaps you can tell a comic genius by the way he/she creates an endless stream of ideas from a few drops of imagination. They think out of the box while staying within allotted rectangles.
This is a reason I believe Jorge Cham may be running out of ideas. It struck to me as odd when he compromised the first rule of comic strips (if there is such a rule): well defined characters and settings. With Tajel's wedding and Slackenerny's promotion to PostDoc, he seems to have resorted to a soap-operatic way of advancing the strip where interludes would have sufficed. This may serve as a bad precedent for his strip.
I don't think Dilbert will ever become a permanent manager. If Watterson were still drawing, Calvin would still be a 6yr old, and the comic would still rock.

